I got my second Moderna vaccination on Wednesday and started having some common side effects on Thursday, including slight nausea, chills, fever, body aches and a very sore arm.

Later I saw an article on line explaining that these side effects are pretty common. It's an indicator that the first vaccine did it's job.

With the second dose, your body not only creates antibodies, but spurs your lymph nodes and other parts of the body to react to the vaccine at the tissue level.

Why does your body create side effects at all? There’s a two-part answer to this question, according to Dr. Richard Kennedy, a professor of medicine at Mayo Clinic and the co-director of the Mayo Clinic Vaccine Research Group.

Your immune system has two different components — innate immunity and adaptive immunity. Innate immunity is your body’s first-line response to an outside invader.

“Innate immunity does the same thing every time it sees a microorganism in your system. It’s got to recognize that you’re infected, sound the alarm and start the adaptive immune response,” Kennedy said.

“Innate immunity is not very good at protecting you against viral infections,” he continued. “It’s more of a speed bump to slow it down.”

After your body’s innate response, which occurs at the first sign of an infection or virus, adaptive immunity takes over. This kind of immunity is responsible for the creation of B and T cells, which can blast away infection.

When you receive a vaccine, your innate immunity is stimulated first. Within a week-and-a-half or so, your adaptive immunity starts firing, offering you actual protection from the virus.

2nd Moderna Thursday. Yesterday, sore arm that had me going for a dose of Advil. Today, still somewhat sore arm, quite tired. Might just have a beer with tonight's corned beef and cabbage...

schweady: "2nd Moderna Thursday. Yesterday, sore arm that had me going for a dose of Advil. Today, still somewhat sore arm, quite tired. Might just have a beer with tonight's corned beef and cabbage...
"

Take Tylenol instead of Advil. Advil supposedly weakens the vaccines immune response.

link

That's a good description. Thanks for sharing it.

Several years back, I was patient 1 in a clinical trial of a vaccine-like cancer therapy. While it didn't work on my cancer, I went through the sort of side effects people are experiencing with their second doses. When the immune system gets triggered into activity, you can feel like crap even if you aren't actually sick. It's an impressive lesson in some of the reasons you feel bad when you are sick.

awbrown: "...Take Tylenol instead of Advil. Advil supposedly weakens the vaccines immune response."
Yeah, that's what my daughter said a week or so ago, so I asked the nurse providing my shot. Using Advil or Tylenol to control pain and fever after the injection is all good, she said. By the time you get the reaction, it's already working.

No reaction other than a tender arm for a couple of days. Just another exciting day at the ranch as far as I was concerned.

Got my second dose of Moderna on Friday. Saturday, especially in the afternoon, I was pretty achy and fatigued. Yesterday I was 100% over it-walked 18 holes of golf with my wife :)

Edit: My pediatrician brother recommends going without acetaminophen or ibuprofen if at all possible.

jhb8426: "No reaction other than a tender arm for a couple of days. Just another exciting day at the ranch as far as I was concerned."
Same here. Second Moderna shot 4 days ago. Only side effect was mild soreness at injection site. My only worry now is non-masked anti-vaccers getting sick and encouraging vaccine resistant variants to evolve.

With our first shots (Moderna, and we're a couple weeks apart because my wife's faster on the computer than I am) we both had the side effect of relief and hope--relief that we got appointments for the vax and hope that COVID will soon be behind us. Tia had a three-hour case of mild chills and a general feeling of fatigue the day after her second Moderna vax. My second is March 25th, and we plan to travel (by RV) west to visit family we haven't seen in over a year...

TZ

I also had a fever for a day after moderna #2, it’s been so long since I was sick I forgot how much that sucks! But it’s nice to be done with it. It’s so good to see case numbers drop. Now I consider it my job to help as many others as I can to get a shot!

awbrown: "I got my second Moderna vaccination on Wednesday and started having some common side effects on Thursday, including slight nausea, chills, fever, body aches and a very sore arm.

Later I saw an article on line explaining that these side effects are pretty common. It's an indicator that the first vaccine did it's job.

With the second dose, your body not only creates antibodies, but spurs your lymph nodes and other parts of the body to react to the vaccine at the tissue level.

Why does your body create side effects at all? There’s a two-part answer to this question, according to Dr. Richard Kennedy, a professor of medicine at Mayo Clinic and the co-director of the Mayo Clinic Vaccine Research Group.

Your immune system has two different components — innate immunity and adaptive immunity. Innate immunity is your body’s first-line response to an outside invader.

“Innate immunity does the same thing every time it sees a microorganism in your system. It’s got to recognize that you’re infected, sound the alarm and start the adaptive immune response,” Kennedy said.

“Innate immunity is not very good at protecting you against viral infections,” he continued. “It’s more of a speed bump to slow it down.”

After your body’s innate response, which occurs at the first sign of an infection or virus, adaptive immunity takes over. This kind of immunity is responsible for the creation of B and T cells, which can blast away infection.

When you receive a vaccine, your innate immunity is stimulated first. Within a week-and-a-half or so, your adaptive immunity starts firing, offering you actual protection from the virus. " Glad you got the shots since we will be seeing you at the Sugar River wing ding. I get my second shot of moderna on the 1st of April. Get ready for a fish fry and hushpuppy fest.

Having had Covid19 (or "the Covid" as my Texas friends say) my first Moderna was like described above for second, and second dose reaction worse than the actual infection. I figure I'm as immune as possible.

billconner: "Having had Covid19 (or "the Covid" as my Texas friends say) my first Moderna was like described above for second, and second dose reaction worse than the actual infection. I figure I'm as immune as possible."

I think I may have had it in early Feb 2020 before it was a "thing". Not much but lots of fatigue for ten days and aloss of smell and taste and exploding foggy head.

No surprise Pfizer 1 made me fall asleep on the drive home with exploding head again ( lucky I did not have to drive myself) and went to bed at 6:30 and slept 12 hours.

Makes me as looking forward to Pfizer 2 as having a root canal.

Awbrown,

Thanks for posting link on using NDAID Advil prior to vaccination. I didn’t know taking an NSAID prior to vaccination may decrease antibody response.

I just got my 2nd Pfizer shot last Thursday and I had been taking Advil daily prior to my 2nd shot.

Wish I had read about the Advil warning prior to getting my shot. Oh well, feeling pretty good and only a sore arm for a couple of days.

Wally13: "Awbrown,


Thanks for posting link on using NDAID Advil prior to vaccination. I didn’t know taking an NSAID prior to vaccination may decrease antibody response.


I just got my 2nd Pfizer shot last Thursday and I had been taking Advil daily prior to my 2nd shot.


Wish I had read about the Advil warning prior to getting my shot. Oh well, feeling pretty good and only a sore arm for a couple of days. "

Just an FYI in the Pfizer and Moderna studies that showed vaccination success rates at 95 and 96% they did not limit or advise people to avoid NSAIDs such as ibuprofen. Not saying the advise to avoid them is wrong...it makes sense...just saying the most current research done specifically for your vaccine dose says you are fine.

T

Interesting article on study of side effects. Summary:

"Young people, women and people who have had the coronavirus report more side effects following COVID-19 vaccinations"

Certainly true for ne, having had ir earlier.

Article

Got the J&J vaccine on the 5th, a Friday. Felt like doo-doo the next day (Saturday.) Felt fine on Sunday.

Mike

First dose Moderna 3-23-21 just a sore arm nothing major for sure, hope the second one is the same.

I got my 2nd Covid/Moderna shot 2 days ago on the White Earth Reservation.
Sore arm, the day after the shot I was really fatigued and had very little appetite. I feel alot better now after the 2nd day. All in all it was not too bad for me.

Got my first Pfizer in December and 2nd one 21 days after that. Sore arm for one day after first, nothing after second shot.

First Moderna February 25th. Arm sore and pressure sensitive at injection site. Second Moderna yesterday at 0915. Had expected chills & fatigue (my wife's 2nd dose symptoms) today, but have only been a bit tired, and have otherwise had a 'normal' day.

TZ

I received my second Pfizer shot on Friday. I woke up Saturday a little achy. I decided to go on my usual long run on Saturday. When I got home I certainly wasn’t 100 percent so I took some Advil and took a short nap. By 2:00 I was feeling fine. Today Sunday, no more side-effects.

1st Moderna - sore arm.

2nd Moderna - sore arm, almost what I’d call a headache, and not very peppy.

First Pfizer shot last Wednesday. Zero side effects, I can’t even feel where she put the needle in.

1st Pfizer on Friday night - painful at the injection site for a day. We’ll see how #2 goes in a few weeks.

Had my second about 3 weeks ago (phizer). Took a precautionary tylenol when I got home. No issues. Wife had her second (phizer) last week. Knocked her down pretty good the next day - headache, fatigue. Next day was fine.

Had my first jab of Astra Zeneca vaccine yesterday at noon. Woke up this morning feeling wiped out. Walked the dog, worked for an hour and went back to bed.

Everyone else I know who had it skated through fine.

What I thought based on comments, possibly true Moderna side effects worse than other vaccines.
Moderna

Got my second Pfizer shot yesterday. Same experience as the first, sore arm, wicked headache, slight stomach discomfort, and all good the following day save a tender injection site.

Got the J&J this morning.

I asked the nurse when to expect the super powers to kick in but she pretended like she didn't know anything about it. I'm hoping for super strength to help with portaging but I'd settle for laser eyes to make fire starting easier during wet conditions.

Anyone else have any new super powers to report or do you prefer to keep them under the radar for now?

I have grown octopus arms. No worry. They're fully retractile and voluntary, so they emerge and disappear on my command.

I live for the moment when somebody says, "Can you give me a hand here?"

And then I give them two hands and eight tentacles. Overkill, huh?

I also like walking down the street and extending and withdrawing my tentacles in a flash and leaving people to wonder if they really saw what they saw. They take a wide berth after everyone else on the street after passing me.

Molly ... LOL ... LOL

I asked the nurse who gave me the vaccine, "am I going to be able to play the piano after this?" She reassured me that I would. I said, "that's great, I never could play one before!"

Still no super powers to report. I did make it out fishing early this morning before the body aches and headache set in. Caught a few small walleye and then headed home when the back started to ache. Nothing too bad just enough to make we want to lay down.

Had my 1st Pfizer April 1st (no fooling’!)
Get my 2nd on 22nd.

It was like having COVID all over again. I asked 3 times if they were sure I should be getting the shot since I just got over the worst of the virus March 20 or so. Oh yes, they said, as long as you aren’t having a mammogram you are just fine.
Same for my man. He got his first shot this past Wednesday, was able to work 4 hours Thursday but has been down for the count since. He’s feeling better today but the chills and then sweats is crazy for him. He said he was cold but his skin was burning hot. No fever though.

My arm still hurts. Why can’t they shoot that into the fat instead of the muscle?

My second dose was last Friday. I was able to keep it from hurting my shoulder too much my constantly moving my arm and not letting it get stiff. It is important to mover your arm constantly the day you get the vaccine. The vaccine is made of some not so pleasant chemicals, and if you just let them sit at the injection site they will damage the surrounding tissue. By moving your arm you are working the vaccine into your system.

My first dose, I did the exact opposite and my arm felt like it was going to fall off. My second dose, it felt like a minor bruise. Tender if touched but otherwise fine as long as I didn't let it get stiff.

As for the other side effects, I did feel pretty sick for about 24-36 hours, starting about 12 hours after getting the injection. The fever and chills hit me pretty hard overnight and I wish I had gone to bed with an extra blanket. I probably would not have been as achy or sore if I had been a bit warmer that night.

So in the end, my advice is move your arm, take Tylenol before you go to bed even if you don't think you need it, have an extra blanket ready, and take it easy the next day. Do this, and you might not even notice many of your symptoms.

When I got a flu shot last fall at my doctor's office, the nurse who gave me the shot massaged the site of the injection pretty vigorously for about 30 seconds. Never felt sore at all.

So I tried this trick with the Covid vaccine shots. Never got a sore arm with shot #1, but was pretty sore for 3-4 days after shot #2 in spite of massaging and moving my arm.

I had my second Pfizer shot yesterday afternoon and so far I just have a sore arm, really no different than what I experienced with my first shot. So far, so good.

my mother had both modernas and we are noticing her memory isn't the same, since the first shot. it changed like the next day. then we found this doctors testimony, on how they are treating it in his clinics blind trial. with ivomectrin and a placebo.. ivomectrin is the only thing that works.

Dr. Ryan Cole

As far as I know Ivomectrin has only been studied directly with COVID in a Petrie dish...according to those studies the amount needed to put into a human to kill COVID would most likely kill more than COVID would...and not by a close amount. Due to the serious side effects most people wouldn’t be able to take it either. Definitely couldn’t be used ont the elderly or most vulnerable. I’d run away from this “Dr.” if he advocates this as a treatment. He sounds like he runs one of those profit medical clinics charging for lab testing that is normally free with your insurance.

Almost everything he said in the video was false BTW. Let’s just look at medical vaccination rates. He stated 50% of health care providers didn’t get vaccinated out of fear of the vaccine. You can find that stat...but it includes anyone in health care. Janitors, maintenance, reception etc...many of whom weren’t offered it at first since they didn’t do direct patient care. Or you can quote low vaccination rates at nursing home employees—many of whom don’t have a high school diploma let alone a college degree.Among frontline face to face health workers the rates vary but many hospitals the rates are above 95%. Among MDs the vaccination rate is 97%.As an MD he has to know this...why did he lie? Or if he doesn’t know this how can ya trust him? That’s just one “fact” he presented...you can do that to almost everything he said.

Also he is one of the 97% of MDs vaccinated or so he says...

T

Thank you t

I’m always so upset with these. With that many mistakes or oversights, I feel comfortable disregarding the rest of it out of hand.

I’ll add I am always advocate for listening to disagreement or questioning policy on both sides. No matter what the subject. That’s how progress occurs. You always need a watch dog. It either strengthens your argument or opens up innovation or ideas to other processes.

What I am really having trouble with this guy is that he presents research that is unproven as fact. There is research on invermectin, there are clinical trials being performed. He misrepresented studies as 100% effective when in any long term study with a high n there is no evidence it does anything. There are more studies going on and and that could change, but taking a case study and presenting it as 100% effective is borderline criminal in my opinion. This medication was never developed for constant long term use as far as I know. I am by no means an expert, but I do know how to read research articles and know the difference between a case study and long term research.

He mentions how good India is doing by being open and using this drug...Google India and COVID...they are doing terrible! It is a just a plain out right lie in the video up above!

The company that manufactures and sells invermectin and could finccially benefit from more wide use has this to say about their drug.
“No scientific basis for a potential therapeutic effect against COVID-19 from pre-clinical studies;
No meaningful evidence for clinical activity or clinical efficacy in patients with COVID-19 disease, and;
A concerning lack of safety data in the majority of studies.“

T