Theoretically, 20-25% for scouts backpacking according to
this great article. But that is just a rough guideline since it is dependent upon so many variables, and portaging rather than backpacking adds even more variables.
How far are you hiking with the pack, how strong is she, how good is the pack at distributing weight comfortably, how heavy is it, etc.? The hips may not even have been as related to the pack weight as to hills, sleeping on the ground, distribution of the weight, etc.
In my wife's case, due to a neck/shoulder injury, she can carry her sleeping bag and clothes and that's about it. And not for very long.
If I had to guess about your wife, I'd suspect a combination of everything you asked. Too much weight for someone of her physical abilities/condition. Age you can't do anything about, but you can lessen the weight, and if she enjoys it she can work at building strength and conditioning.
I've reached the age where I realize that if I want to continue doing the things I want to do, I need to put some effort into staying in condition. I suspect that 10 years from now, I'll have to work even harder at it, just to maintain less ability.